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List of Treatments for Melanoma

Below is a listing of treatments and therapies for melanoma. Click on one to read more information or connect with others currently using it.

Amputation

Overview
Amputation — the surgical removal of a body part like a finger or toe — is a very rare but sometimes necessary treatment for melanoma, particularly when the cancer has advanced or recurred. This surgery is…

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Amtagvi (Lifileucel)

Overview
Amtagvi is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with unresectable (cannot be removed by surgery) or metastatic melanoma (melanoma that has spread) who have…

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Braftovi (Encorafenib)

Overview
Braftovi is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to be used in combination with binimetinib to treat people who have unresectable or metastatic melanoma with a BRAF…

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Chemotherapy

Overview
Chemotherapy is a treatment with drugs to eliminate cancer cells. Chemotherapy is usually only considered for advanced melanoma, after other treatments have been tried. It's not commonly the first choice for…

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Clinical Trials

Overview
Depending on certain factors, you might qualify for clinical trials studying new melanoma treatments. These trials are crucial for advancing our understanding of melanoma and evaluating novel therapies. If you…

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Cotellic (Cobimetinib)

Overview
Cotellic is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat advanced melanoma. This type of melanoma can’t be removed by surgery, has spread to other parts of the body…

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High-Dose Interferon Alfa-2b (Intron A)

Overview
Intron A is approved by the U.S. Food and Drug Administration (FDA) for treatment for melanoma, along with several other health conditions. For melanoma, it’s specifically indicated as adjuvant to surgical…

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Imlygic (Talimogene Laherparepvec)

Overview
Imlygic is approved by the U.S. Food and Drug Administration (FDA) for the local treatment of unresectable (inoperable) cutaneous, subcutaneous, and nodal (lymph node) lesions in people with melanoma that has…

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Keytruda (Pembrolizumab)

Overview
Keytruda is approved by the U.S. Food and Drug Administration (FDA) for the treatment of individuals with unresectable (inoperable) or metastatic melanoma, as well as for the adjuvant (post-surgical) treatment of…

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Kimmtrak (Tebentafusp-Tebn)

Overview
Kimmtrak is a medication that has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults living with HLA-A*02:01-positive unresectable or metastatic uveal melanoma. Unresectable…

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Mekinist (Trametinib)

Overview
Mekinist is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat people who have unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as identified by an…

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Mektovi (Binimetinib)

Overview
Mektovi is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to be used in combination with encorafenib to treat people who have unresectable or metastatic melanoma with a BRAF V600E or…

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Mohs Surgery

Overview
Mohs surgery, also known as Mohs micrographic surgery, is a surgical procedure to treat various types of skin cancer, including basal cell carcinoma and squamous cell carcinoma. Mohs surgery is not an effective…

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Opdualag (Nivolumab and Relatlimab-Rmbw)

Overview
Opdualag is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults and children 12 years of age or older with melanoma that has spread or cannot be removed…

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Opvido (Nivolumab)

Overview
Opvido is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various types of cancer, including for adults and children 12 and up living with unresectable (inoperable) melanoma or…

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Proleukin (Aldesleukin)

Overview
Proleukin, approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with metastatic melanoma, which is melanoma that has spread to other parts of the body. Proleukin is also known by…

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Radiation Therapy

Overview
Radiation therapy is a treatment method that uses high-energy rays or particles, like X-rays, to kill cancer cells. While it’s not commonly used for treating melanoma skin cancer, there are specific situations…

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Sylatron (Peginterferon Alfa-2b)

Overview 
Sylatron is approved by the U.S. Food and Drug Administration (FDA) for treating melanoma with microscopic or gross nodal involvement following surgery to remove the cancer. Sylatron is also known by its drug…

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Tafinlar (Dabrafenib)

Overview
Tafinlar is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat melanoma that has specific genetic mutations (changes). Tafinlar can be taken alone to treat melanoma that…

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Tecentriq (Atezolizumab)

Overview
Tecentriq is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with BRAF V600 mutation-positive unresectable (inoperable) melanoma or metastatic melanoma (melanoma that has…

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Tecentriq Hybreza (Atezolizumab and Hyaluronidase-Tqjs)

Overview
Tecentriq Hybreza is approved by the U.S. Food and Drug Administration (FDA) in combination with cobimetinib and vemurafenib for the treatment of adults with BRAF V600 mutation-positive unresectable or metastatic…

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Vitrakvi (Larotrectinib)

Overview
Vitrakvi is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat children and adults with solid tumors that have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion…

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Wide Excision

Overview
Wide excision — also known as wide local excision ‚ is a surgical procedure used to treat melanoma. It entails removing a tumor along with a margin of healthy skin and tissue around it. The primary goal is to…

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Yervoy (Ipilimumab)

Overview
Yervoy, approved by the U.S. Food and Drug Administration (FDA) for the treatment of melanoma, is indicated for treating adults and children 12 years and older with unresectable (inoperable) or metastatic…

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Zelboraf (Vemurafenib)

Overview
Zelboraf is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of advanced melanoma that can’t be removed by surgery, has spread to other parts of the body, and is…

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