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5 Signs Melanoma May Be Returning: Fatigue, Stomach Pain, and More

Written by Ted Samson
Posted on January 29, 2025

A new study identified five key symptoms that melanoma may be recurring (returning). Researchers reviewed data from individuals with a history of skin melanoma and found that among the 189 people who experienced cancer recurrence:

  • Twenty-three percent experienced fatigue.
  • Nineteen percent had lymph node enlargement.
  • Nine percent observed changes in appetite.
  • Eight percent developed abdominal pain.
  • Seven percent reported shortness of breath.

Monitoring Is Key

Detecting recurrence early can improve outcomes and reduce complications. Although most melanoma recurrences are symptomatic, up to 32 percent of recurrences occur without symptoms, often detected through imaging or physician-led evaluations. That’s why it’s important not only to know what symptoms to look for but also to attend all recommended follow-up appointments for monitoring exams.

If you or a loved one has had melanoma, it’s important to discuss any new or unusual symptoms with your healthcare provider right away.

Learn more about melanoma prognosis, survival rates, and life expectancy.

Find Your Team

On MyMelanomaTeam, the social network for people living with melanoma and their loved ones, members come together to ask questions, give advice, and share their stories with others who understand life with melanoma.

Have you noticed symptoms like fatigue or lymph node changes since completing melanoma treatment? Have you discussed these with your cancer care team? Share your tips and experiences in a comment below, or start a conversation on your Activities page.

Ted Samson is a copy editor at MyHealthTeam. Learn more about him here.
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