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Has Anyone Else Developed Inflammatory Arthritis As Side Effect Of Immunology Treatment?

A MyMelanomaTeam Member asked a question đź’­
Hudson, MA

3 treatments combination ipi/nivo. Trying steroids now ? dmards?

October 9
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A MyMelanomaTeam Member

Update: Went on steroids (high dose) with some improvement in swelling/pain but not enough. I am now taking Methotrexate for Arthritis and reducing Steroid dosage. After only a few weeks, I am feeling much improved and starting on a single drug (nivolumab) next week.

November 11
A MyMelanomaTeam Member

Inflammatory arthritis can indeed be a side effect of immunotherapy treatments for melanoma, such as the combination of ipilimumab (ipi) and nivolumab (nivo). These treatments can activate the immune system, sometimes leading to immune-related adverse effects, including inflammatory arthritis.

- Steroids: Often used to Show Full Answer

Inflammatory arthritis can indeed be a side effect of immunotherapy treatments for melanoma, such as the combination of ipilimumab (ipi) and nivolumab (nivo). These treatments can activate the immune system, sometimes leading to immune-related adverse effects, including inflammatory arthritis.

- Steroids: Often used to manage immune-related side effects by reducing inflammation.
- DMARDs (Disease-Modifying Antirheumatic Drugs): These may be considered if steroids are not sufficient or if long-term management is needed.

It's important to discuss these options with your cancer care team to tailor the treatment to your specific needs.

October 9

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